Life on a GLP-1: eating, exercise and injections
Day-to-day life on semaglutide or tirzepatide in Australia: protein, muscle, Christmas in summer and Ramadan, missed doses, storing pens in the heat, and getting rid of needles safely.
Life on a GLP‑1 means eating less, but eating well. Get protein at every meal, eat small portions slowly, drink enough and do strength exercise to keep muscle. Inject on the same day each week, keep pens in the fridge until you start them, and put used needles in a sharps container. Keep pens below 30 °C in summer. Expect regular reviews. Talk to your doctor before starting, stopping or changing a dose.
Key facts
- Protein
- 1.2–1.6 g per kg a day has been proposed during weight loss, or a flat 80–120 g a day1
- Exercise
- Strength training at least 3 times a week, plus 150 minutes of brisk activity1
- Missed weekly dose
- Semaglutide: within 5 days of the missed dose. Tirzepatide: unless your next dose is under 3 days away. Never take two doses together.3,5
- Needles
- Into a sharps container or a puncture-proof container, then to a drop-off point your pharmacy or council can name17
- Review
- Regular reviews against targets you set with your doctor, often 10–15% for weight14
On this page
- What should I eat on a GLP‑1?
- How do I keep my muscle?
- What about Christmas, Ramadan and other fasts?
- How do I inject, and what if I miss a dose?
- How do I store it in the heat, and travel with it?
- How do I know if it's working?
- What should I keep track of?
- What about food noise and family meals?
- Questions people ask
What should I eat on a GLP-1?
Smaller meals with protein first. You will eat less, so each bite needs to count for protein, fibre and fluids.
A 2025 advisory from four US nutrition and obesity groups proposes 1.2–1.6 g of protein per kg of body weight a day during weight loss.1 The everyday minimum for adults is 0.8 g per kg.1
For a 90 kg (198 lb) person, that works out to 108–144 g a day.1 But using your full body weight can overestimate what you need.1 So the same advisory offers a simpler goal: 80–120 g a day.1 It also warns against staying at 2 g per kg or more for long.1 If you have kidney disease, ask your doctor before eating more protein.
Eating the protein part of your plate first helps you finish it before you feel full.1 The advisory favours beans and lentils, dairy, fish, eggs and chicken. It suggests keeping red and processed meat low.1
Protein in everyday foods
We worked out each serving from the UK's official food tables (McCance and Widdowson's, known as CoFID).2 Australian products may differ a little, so check the nutrition panel on the pack. Each line says whether the food is weighed raw, cooked or from a can.
- Red lentils30 g dried8 g
- Chickpeas120 g canned, drained10 g
- Red kidney beans120 g canned, drained10 g
- Baked beans200 g, in tomato sauce10 g
- Edamame80 g frozen, boiled10 g
- Tofu100 g, steamed8 g
- Quorn pieces100 g, as bought14 g
- Peanuts, plain30 g8 g
- Greek-style yogurt, plain150 g9 g
- Cottage cheese, plain100 g9 g
- Quark100 g15 g
- Cheddar30 g8 g
- Reduced-fat milk200 g (about 200 ml)7 g
- Egg, boiled1 medium, 50 g7 g
- Chicken, white meat100 g raw24 g
- Tuna, canned in brine100 g drained25 g
- Beef mince100 g raw20 g
- Salmon, farmed100 g raw20 g
- Cod100 g raw18 g
Source: McCance and Widdowson's Composition of Foods Integrated Dataset 2021, protein per 100 g, multiplied up to each serving and rounded to whole grams.2
A worked example: 100 g chicken, 150 g Greek-style yogurt and 200 g baked beans add up to about 43 g of protein.2 That is just over half of the 80 g goal.
Smaller meals, fibre and fluids
- Small meals. Vomiting is more likely after a large meal.1
- If you feel sick: try a small breakfast, then small meals every 3–4 hours.1
- Fibre, slowly. Go easy on high-fibre food in the first few days. After that, add fibre gradually to prevent constipation.1
- Fluids. Losing fluids through vomiting or diarrhoea can harm your kidneys.1,7 The advisory says to drink enough fluids.1 For alcohol, see Questions people ask.
How do I keep my muscle?
Do strength exercise at least 3 times a week, and eat enough protein. Walking alone protects less muscle than walking plus strength training.1
Not all the weight you lose is fat. In one semaglutide trial, of every 10 kg (about 22 lb) lost, about 4 kg was "lean mass": muscle and other non-fat tissue. About 2 kg of that was muscle.1
The 2025 advisory suggests strength training at least 3 times a week, plus at least 150 minutes of moderate activity, like brisk walking.1 The plan should match your fitness level.1
One example week, not a prescription: 3 strength days and 150 minutes of walking, as in the 2025 advisory.1 Pick one injection day you'll remember, and use the same day each week.3
What about Christmas, Ramadan and other fasts?
Big meals make vomiting more likely, so take small plates and stop early.1 Fasting needs a plan, especially if you take insulin or a sulfonylurea (a type of diabetes tablet, such as gliclazide).8,13
Christmas, barbecues and big meals
Christmas lunch, summer barbecues, office parties, weddings, Eid and Diwali meals all follow the same rules:1
- Small portions, eaten slowly, with the protein first.1
- Fewer rich, fried and sweet dishes.1
- Keep alcohol to a minimum.1
- You don't have to finish what you're served, or have a second helping to be polite.
If your injection day lands on a big day and you'd rather move it, you can, as long as there are at least 3 days between two doses.4,5 Christmas here falls in summer, so drink enough on hot days, and keep your pen out of hot cars and away from the beach bag: see storage.
Ramadan
The main international guidance is the 2021 Ramadan guidelines from the International Diabetes Federation and the Diabetes and Ramadan International Alliance (IDF-DAR).11,12 Advice written for UK pharmacists in July 2026 builds on them:13 About 3 in 100 Australians are Muslim.20
- GLP‑1 medicines can be used while fasting, if taken on schedule with a doctor's oversight.11,12 Don't stop without medical advice.11
- Finish dose increases first. That advice is to complete them at least 4 to 6 weeks before a planned fast, and to put off the next increase if the fast starts soon.13
- Weekly injections stay on the same day each week. Some people inject after iftar to limit nausea, others after suhoor to stay full through the day.13
- Watch for constipation and dehydration, especially when Ramadan falls in hot weather. Fasting raises the risk of these, and of missing nutrients. Fill the eating window with wholegrains, pulses, fruit, vegetables and enough fluids.13
- The research is mostly on older GLP‑1 medicines (liraglutide, lixisenatide and exenatide). The 2021 guidelines don't name semaglutide or tirzepatide, and say more research is needed.12
Other fasts
We found no Australian guidance written for GLP‑1 users during other religious fasts, such as Yom Kippur, Lent, Navratri or Karva Chauth. The same pharmacy advice applies to any planned fast: finish dose increases weeks before, and plan your fluids.13
How do I inject, and what if I miss a dose?
Inject once a week, on the same day, into your belly, thigh or upper arm. Use a new needle and a new spot each time.
- Where: just under the skin of the belly, thigh or upper arm.3,5 For Mounjaro, the back of the upper arm is for someone else to inject.5
- When: any time of day, with or without food.3,5
- Rotate: use a different spot each week.5
- Needles: a new needle every time. Don't store the pen with a needle on.8
- Never share a pen, even with a new needle. It can spread serious infection.8
Getting rid of needles and pens
- Use a sharps container, or a strong puncture-proof container with a lid, and put used needles straight in.17
- When it's full, ask your pharmacy, GP or local council where to drop it off. Arrangements vary between states and councils.
- Don't put loose needles in household or recycling bins. In New South Wales, the needle clean-up hotline is 1800 633 353.17
- Pen needles. The National Diabetes Services Scheme gives free pen needles to registered people who use insulin; we couldn't confirm whether that covers people on a GLP‑1 alone.18
Missed a dose?
Never take two doses to catch up. The Australian product information says to skip a late dose and carry on as normal on your usual day.3,5 If you've missed more than one dose, ask your doctor before restarting. The Wegovy label says a lower restarting dose should be considered.3
On tablets?
- Rybelsus (for type 2 diabetes) is taken on an empty stomach, followed by a 30-minute wait.9 We found no GLP‑1 tablet approved for weight in Australia as of October 2026.
How do I store it in the heat, and travel with it?
Keep unopened pens in the fridge. Once in use, most can sit outside the fridge for a few weeks, but only below 30 °C.
Store new pens at 2–8 °C, away from the cooling element. Never freeze them, and never use one that has frozen.3,4,5 Keep the cap on to protect the pen from light.3
From the Australian product information. Always follow the Consumer Medicine Information leaflet in your own pack.
Travelling. Diabetes UK's advice for insulin, which also needs fridge storage, fits here. Carry it in hand luggage, because the hold gets very cold and bags get lost.10 A cool bag helps, but don't let the pen touch frozen ice packs.10 Some airlines ask for a doctor's letter, so carry your prescription.10
How do I know if it's working?
Expect regular reviews. Australian guidance sets weight-loss targets with you and changes the plan if they aren't reached.14
- Week 0Start on a low dose. Write down your weight and waist.
- Every 4 weeksThe dose usually steps up, if side effects allow. If stomach side effects are bad, the next step can wait.3,5
- At reviewsCheck against your target. The Australian algorithm suggests 10–15% weight loss for many people, and stepping up or changing the plan if it isn't reached.14 For teenagers on Wegovy: stop if BMI hasn't fallen 5% after 12 weeks on the full dose.3
- After thatRegular reviews, for as long as you take it. The algorithm says weight-loss medicines will usually be needed long term.14
For a 90 kg (198 lb) person, 10% is 9 kg, about 20 lb. Falling short doesn't mean you failed; smaller losses still help, especially for preventing diabetes.14 Your doctor weighs up the benefits and risks of carrying on. Guide 3 covers the other options.
On the older daily medicine liraglutide (Saxenda, and its generic copies), the label is stricter: stop after 12 weeks on the full 3 mg dose if you haven't lost at least 5%.15 And none of these medicines replaces diet and exercise: they're approved as an add-on to a reduced-energy diet and more activity.3,5
What should I keep track of?
Your weight, waist and side effects, and your sugar if you have diabetes. Bring the notes to each review.
- Weight and waist: write them down, so you can compare at your reviews. Guide 1 shows how to measure your waist.
- Blood sugar, if you have diabetes: check before you start and while you take it.7 Low sugar can show as dizziness, sweating, shaking, blurred vision, confusion or a fast heartbeat.7
- Doctor checks: your heart rate, because your resting pulse can rise on these medicines. Tell your doctor if your heart races while you are resting.7 Kidney tests if you've had bad vomiting or diarrhoea.7 If you have diabetes, report any change in your eyesight: a fast improvement in blood sugar can briefly worsen diabetic eye disease (retinopathy).7
- Side effects and meals: note what you ate before nausea. Patterns help.
- Report side effects to the TGA, or ask your doctor or pharmacist to. Anyone can report.16
What about food noise and family meals?
Many people find the constant thoughts about food go quiet. Some also lose the pleasure of eating, and that can feel strange at family meals.
Don't skip meals for hours because you aren't hungry. Getting very hungry can bring back cravings for sweets and refined carbs.1
At home, it helps if the people you eat with know why your plate is smaller. A simple line works: "I'm on a medicine that fills me up fast. I'll have a little of everything."
Questions people ask
Can I drink alcohol on a GLP-1?
The 2025 US nutrition advisory says to keep alcohol to a minimum.1
Can I change my injection day?
Yes, as long as there are at least 3 days between two doses. This is in the Australian product information for Ozempic, Wegovy and Mounjaro.4,5
My pen froze in the fridge. Can I still use it?
No. The labels say not to use a pen that has been frozen.3,5 Keep pens away from the cooling element at the back of the fridge.3,4
My pen got warm in the car or on holiday. Can I still use it?
The labels allow time out of the fridge only at or below 30 °C.3,5 Time at room temperature below 30 °C counts towards the days allowed in the storage list.3,5 The labels don't say what to do after a pen has been hotter than 30 °C, so ask your pharmacist before you use it.
I take the contraceptive pill. Does it matter?
With tirzepatide (Mounjaro), yes. Its product information advises switching to a non-pill method or adding a barrier method, such as condoms, for 4 weeks after starting and for 4 weeks after each dose increase.5
Where do I put used needles?
In an approved sharps container, or a strong puncture-proof container with a lid.17 When it's full, ask your pharmacy, GP or council where to drop it off; arrangements vary between states and councils. Don't put loose needles in household or recycling bins.
I have an operation or endoscopy coming up. What should I do?
Tell every doctor involved that you take a GLP-1. Australian anaesthetists advise most people to keep taking it, with clear fluids only for the 24 hours before, then the usual 6-hour fast.21
Before you move on
- Protein first, at every meal. Small portions, eaten slowly.
- Strength exercise at least 3 times a week to protect muscle.
- Missed dose: 5 days for semaglutide, 4 for tirzepatide. Never double up.
- Never freeze a pen, and never keep it above 30 °C.
- Used needles go in a sharps bin, never the household bin.
- Fasting for Ramadan? Finish dose increases weeks before, and plan with your doctor.
- Expect a review at about 6 months.
Sources
- Mozaffarian D et al. Nutritional priorities to support GLP-1 therapy for obesity: a joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association and The Obesity Society. Am J Clin Nutr 2025;122:344–367 (also published in Obesity). Declared interests: 4 of 18 authors declare advisory or speaker roles with Novo Nordisk and 5 with Eli Lilly (paper's own declaration). PMC12612741 · doi:10.1002/oby.24336
- Public Health England (now on GOV.UK). McCance and Widdowson's The Composition of Foods Integrated Dataset (CoFID) 2021, table 1.3 Proximates, protein per 100 g: lentils, red, split, dried, raw 25.6; chick peas, canned, re-heated, drained 8.4; red kidney beans, canned, re-heated, drained 8.6; baked beans in tomato sauce 5.0; edamame, frozen, boiled 12.2; tofu, steamed 8.1; Quorn pieces 14.0; peanuts, plain 25.8; Greek style yogurt, plain 5.7; cottage cheese, plain 9.4; quark 14.6; Cheddar, English 25.4; semi-skimmed milk 3.5; egg, boiled 14.1; chicken, light meat, raw 24.0; tuna, canned in brine, drained 24.9; beef mince, raw 19.7; salmon, farmed, raw 20.4; cod, raw 17.5. Updated 19 March 2021. Link
- Novo Nordisk. Wegovy (semaglutide) Australian Product Information, revised 22 June 2026 (sections 4.1, 4.2, 4.4, 4.6, 4.8, 6.4). medsinfo.com.au
- Novo Nordisk. Ozempic (semaglutide) Australian Product Information, revised 25 September 2026 (sections 4.1, 4.2, 4.6, 6.3). medsinfo.com.au
- Eli Lilly. Mounjaro (tirzepatide) Australian Product Information, version A14.0, October 2026 (sections 4.1, 4.5, 4.6, 6.4). medsinfo.com.au
- Eli Lilly. Trulicity Australian Product Information, section 6.4 (may be kept unrefrigerated for up to 14 days at up to 30°C). Revised 28 May 2026. medsinfo.com.au
- Novo Nordisk. Wegovy (semaglutide) US prescribing information and medication guide, revised June 2026. PDF
- Novo Nordisk. Ozempic (semaglutide) US prescribing information, medication guide and instructions for use, revised May 2026. PDF
- Novo Nordisk. Rybelsus (oral semaglutide) US prescribing information, revised January 2026. PDF
- Diabetes UK. Travelling with diabetes. Updated 24 March 2026. Link
- Alayed KM. Glucagon-like peptide-1 (GLP-1) during Ramadan: narrative review of the published literature. J Obes, 2023. doi:10.1155/2023/8626081
- Hassanein M et al. Diabetes and Ramadan: practical guidelines 2021 (IDF-DAR). Diabetes Res Clin Pract, 2022;185:109185. doi:10.1016/j.diabres.2021.109185. Full guidelines (IDF with the DAR International Alliance, 2021), chapter 15: PDF
- Carvalho A. Fasting and weight-loss medications: what to advise your patients (citing IDF-DAR 2021 and the South East London Area Prescribing Committee). The Pharmacist, 29 July 2026. Link
- Markovic TP, Proietto J, Dixon JB et al. The Australian Obesity Management Algorithm. Australian Diabetes Society, with ANZOS, ANZMOSS and the RACGP, July 2024. diabetessociety.com.au
- Novo Nordisk. Saxenda Australian Product Information, section 4.1 ("should be discontinued after 12 weeks on the 3.0 mg/day dose if a patient has not lost at least 5% of their initial body weight"). Revised 26 June 2026. medsinfo.com.au
- Therapeutic Goods Administration. Reporting adverse events: consumers (report online, or ask your doctor or pharmacist to report). Updated 2 September 2026. tga.gov.au
- NSW Health. Community sharps disposal ("store your used sharps in a puncture-proof container"; needle clean-up hotline 1800 633 353). health.nsw.gov.au
- National Diabetes Services Scheme (NDSS). Pen needles and syringes ("If you are registered with the NDSS and use insulin, you can access free pen needles and syringes"). ndss.com.au
- Healthdirect Australia. How healthdirect can help you ("call triple zero (000) for an ambulance immediately"; helpline 1800 022 222). healthdirect.gov.au
- Australian Bureau of Statistics. 2021 Census shows changes in Australia's religious diversity (Islam 813,392 people, 3.2%; Hinduism 684,002 people, 2.7%). 28 June 2022. abs.gov.au
- ANZCA, with the Australian Diabetes Society, GESA and NACOS. Clinical practice recommendations regarding patients taking GLP-1 receptor agonists ("continue these medications"; 24-hour clear-fluid diet, then the standard six-hour fast). anzca.edu.au
Last checked 12 Oct 2026 · Next review due Jan 2027 · Report an error
How this guide was made. Written by the GLP Guidebook team from the sources above: Australian product information, Australian and international guidance, published research, and named reports. It's general information, not medical advice. Talk to your GP or another qualified prescriber before starting, stopping or changing any medicine. In an emergency, call triple zero (000). For health advice any time, call healthdirect on 1800 022 222. Report suspected side effects to the TGA. How we write