Is Zepbound available in Canada?
Yes. Health Canada approved Zepbound (tirzepatide) for weight management on 13 May 2025, and it went on sale on 9 July 2025. In June 2026 it was also approved for moderate to severe sleep apnea in adults with obesity. In Canada it comes as a KwikPen holding 4 weekly doses, on prescription.
- Every GLP‑1 medicine is a prescription drug in Canada. A doctor, nurse practitioner or other authorized prescriber must assess you first.1
- Prices here are official list or formulary prices, with the date we checked them. We never quote a pharmacy's, clinic's or savings card's price, and we don't name or rank sellers.
- Canadian law bans advertising a drug to the public as a treatment for obesity or diabetes. This page is information, not an ad, and nothing here is for sale. The risks are in Guide 5: Side effects and risks.
Who is Zepbound approved for?
Zepbound is approved for adults with a BMI of 30 or more, or 27 to 30 with at least one weight-related condition, alongside diet and activity.2
Since June 2026 it is also approved for moderate to severe obstructive sleep apnea in adults with a BMI of 30 or more. Lilly called it the first medicine approved in Canada for that use.2,3 It shouldn't be combined with Mounjaro or any other GLP‑1 medicine.2 Canada's obesity guideline lists tirzepatide 5, 10 or 15 mg among the medicines to offer at a BMI of 30, or 27 with weight-related complications.4 A KwikPen can be kept out of the fridge for up to 30 days at no more than 30 °C, and must never be frozen.2
How is Zepbound different from Mounjaro?
It is the same medicine, tirzepatide, under a different name and approval: Zepbound for weight and sleep apnea, Mounjaro for type 2 diabetes.2,5
In Canada both come as multi-dose KwikPens, each holding 4 weekly doses.2,5 More in Is Mounjaro approved for weight loss in Canada?
What does Zepbound cost, and who pays?
The reported list price is $300 for 4 weeks at 2.5 or 5 mg and $420 at 7.5 or 10 mg, the same as Mounjaro, from 29 December 2025.6
No public drug plan covers Zepbound for weight management, as of 12 October 2026. Some private plans do, usually with forms or conditions. Prices and arithmetic are in How much is Mounjaro in Canada? Fake tirzepatide is sold online: Health Canada warned in 2025 that "peptides" including tirzepatide sold by one website were illegal.7 Only a pharmacy pen with a DIN is approved.8
- Stomach effects are very common. In the weight trials on the Canadian Zepbound monograph, 25 to 29 in 100 people on 5 to 15 mg felt sick (nausea), against 9 in 100 on placebo.2
- Gallbladder inflammation (cholecystitis) was reported in 0.6 in 100 people on Zepbound and 0.2 in 100 on placebo.2
- The pill. Tirzepatide can make the contraceptive pill less reliable. The monograph advises switching to another method, or adding a barrier method, for 4 weeks after starting and after each dose increase.2
- Who shouldn't take it. Not for anyone with a personal or family history of medullary thyroid cancer or MEN 2. Mounjaro's monograph says not to use it in pregnancy.2,5
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Related questions
Sources
- Health Canada. Drug Product Database: product records and marketing status for semaglutide and tirzepatide products (for example Ozempic DIN 02471469 "Marketed"; Sevmia DIN 02569582 "Approved", not marketed; Zepbound first marketed 9 July 2025). Searched 12 Oct 2026. health-products.canada.ca
- Eli Lilly Canada. Zepbound (tirzepatide injection) Product Monograph, 11 Jun 2026 (indications: BMI 30 or more, or 27 to under 30 with a weight-related condition; moderate to severe obstructive sleep apnea in adults with BMI 30 or more; nausea 24.6–29.0% on 5–15 mg vs 8.5% on placebo; cholecystitis 0.6% vs 0.2%; oral contraceptives: switch or add a barrier method for 4 weeks after starting and after each dose increase; "The ZEPBOUND multi-dose KwikPen contains 4 doses"; unrefrigerated up to 30 °C for up to 30 days; do not freeze; discard "in a puncture-resistant container, or in accordance with local requirements"; not recommended with other tirzepatide products or GLP-1 RAs). pdf.hres.ca (PDF)
- Eli Lilly Canada. Health Canada approves Zepbound as the first-ever obstructive sleep apnea medication in Canada for adults living with obesity. Press release, 16 Jun 2026. lilly.com
- Pedersen SD, Manjoo P, Dash S, et al. Canadian Adult Obesity Clinical Practice Guideline: Pharmacotherapy for Obesity Management in Adults, 2025 update. Obesity Canada, version 3, 11 Aug 2025 (Rec 1: waist measures and "ethnicity-specific BMI thresholds"; Rec 3: medicines "should be offered to individuals with BMI ≥ 30 kg/m2 or BMI ≥ 27 kg/m2 with adiposity related complications"; compounded products not to be used). obesitycanada.ca (PDF)
- Eli Lilly Canada. Mounjaro (tirzepatide injection) Product Monograph, 23 Jun 2026 (indication: glycemic control in adults with type 2 diabetes and ages 10 to under 18 with type 2 diabetes; nausea 12.2–18.3% on 5–15 mg vs 4.3% on placebo; contraindicated in pregnancy; KwikPen "delivers four doses", up to 30 days unrefrigerated at no more than 30 °C; single-dose pen or vial up to 21 days; do not freeze; discard "in a puncture-resistant container or in accordance with local requirements"). pdf.hres.ca (PDF)
- Benefits and Pensions Monitor. Eli Lilly drops Canadian Mounjaro, Zepbound list prices to $300 for starting doses, 19 Dec 2025 (reporting Reuters and The Globe and Mail: $300 per 4-week supply for 2.5 and 5 mg and $420 for 7.5 and 10 mg from 29 Dec 2025; Reuters "could not immediately verify the report"). benefitsandpensionsmonitor.com
- Health Canada. Unauthorized injectable peptide drugs seized and sold… may pose serious health risks. Advisory, 1 Aug 2025 (tirzepatide and retatrutide among the products; "Selling unauthorized drugs is illegal in Canada"). recalls-rappels.canada.ca
- Health Canada. Thinking about buying GLP-1 drugs like Ozempic or Mounjaro? Beware of fake or unauthorized products. Advisory, 21 Jan 2026 ("Only buy prescription drugs from licensed pharmacies"; check the "eight-digit Drug Identification Number (DIN)"; sellers "both in stores and online"; misused logos and "fake endorsements"; report suspected counterfeit products). recalls-rappels.canada.ca
Last checked 12 Oct 2026 · Next review due 12 Apr 2027 · Report an error
How this answer was made. Written by the GLP Guidebook team from the sources above, all checked on 12 Oct 2026. Prices are official list or formulary prices, never a seller's, savings-card or coupon price, and we don't name or rank sellers. Availability, coverage and recall facts are dated because they change. Figures marked as our arithmetic are worked out from those sources. It's general information, not medical advice, and not an advertisement for any medicine. Talk to a doctor, nurse practitioner or pharmacist before starting, stopping or changing any medicine. How we write