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How do you inject Mounjaro with the KwikPen, and use the Ozempic pen?

Each maker's instructions, step by step: priming, air bubbles, the dose counter, injection sites and used needles.

Written for India. Reading from the US? US versionComing soon

The short answer

Lilly's instructions say to fit a new needle and prime the Mounjaro KwikPen before every weekly dose. Then turn the knob until it stops, push, and count to 5. The Ozempic pen needs a flow check only with each new pen, and a 6-second hold. The leaflets name the belly or thigh, a new spot each week.

Key takeaways

  • The Mounjaro KwikPen instructions say to fit a new needle and prime the pen before every weekly injection, then count to 5 while pushing.1
  • The Ozempic pen instructions say to check the flow only before the first injection with each new pen, then hold the button for 6 seconds.5
  • The Mounjaro KwikPen holds 4 weekly doses, and its instructions say to throw it away after the fourth dose, even with medicine left.1
  • India's Solid Waste Management Rules 2026 class used needles and syringes from homes as "special care waste", kept apart from other rubbish.17
  • We found no Indian instructions leaflet online for Mounjaro, Ozempic or Wegovy, so this post uses the US and EU leaflets and says which.1,5,8
Before you go further
  • GLP‑1 medicines are prescription-only in India, not sold over the counter.19
  • A government statement on 1 Apr 2026 said only endocrinologists, internal-medicine specialists and cardiologists can prescribe them.19 CDSCO expert-committee minutes attach a similar condition to some approvals (endocrinologist or internal-medicine specialist), but we found no rule covering every brand.20,21
  • The labels say a doctor or nurse should train you on your own pen or vial first.4,5 This page is a reading aid for that leaflet, not a replacement.
  • Every pen carries the same risks as the medicine inside: Guide 5.
  • We name brands only to describe their instructions. Nothing here recommends a brand.
On this page
  1. Which pens and vials are sold in India, and is there an Indian leaflet?
  2. What do the Mounjaro KwikPen instructions say, step by step?
  3. Why does the KwikPen need priming every week, and what about air bubbles?
  4. How do the instructions say to inject from a Mounjaro vial?
  5. What do the Ozempic pen instructions say, step by step?
  6. How is the Wegovy FlexTouch pen different?
  7. Where do the instructions say to inject, and how do you rotate?
  8. How do you get rid of used needles and pens in India?
  9. How long does a pen last once you start it?
  10. Questions people ask
  11. How we researched this

Which pens and vials are sold in India, and is there an Indian leaflet?

India has the Mounjaro KwikPen, Mounjaro single-dose vials, the Ozempic pen and Wegovy FlexTouch pens. We found no Indian instructions leaflet for any of them online.9,11,12,15

Lilly launched Mounjaro in India in March 2025 as 2.5 mg and 5 mg single-dose vials.9,10 The KwikPen followed in August 2025, in six strengths from 2.5 mg to 15 mg.9 Pharmacy listings in October 2026 still show single-dose vials next to the KwikPen.11

Novo Nordisk sells Ozempic in India at 0.25 mg, 0.5 mg and 1 mg, in a pen.14,15 Wegovy came in June 2025 in five strengths, also in a pen.13 A 2025 CDSCO alert names Indian Wegovy 0.25 mg, 0.5 mg and 1 mg pens as "Wegovy FlexTouch".12

Product in IndiaWhat it isInstructions this post uses
Mounjaro KwikPenA multi-dose pen with 4 fixed weekly doses1,9US KwikPen leaflet (Jan 2026); the EU one has the same steps1,7
Mounjaro vialOne weekly dose, drawn up with a syringe3,10US single-dose vial leaflet (Apr 2026)3
Ozempic penA dial-a-dose pen with a dose counter5US 0.25 mg / 0.5 mg pen leaflet (Jun 2026)5
Wegovy FlexTouchA dial pen; in the EU, each one holds 4 doses of one strength8,12US FlexTouch leaflet (Jun 2026) and the EU leaflet6,8

The US also sells Mounjaro single-dose pens. Indian pharmacy listings don't show them, so we use their leaflet only where it answers a common question. Checked 5 Oct 2026.

Generic semaglutide makers sell their own reusable pens and vials.14 Each has its own leaflet, and we did not review them. The leaflet in your own box is the one that counts. Our post on semaglutide generics lists who makes what.

What do the Mounjaro KwikPen instructions say, step by step?

The instructions say: check the pen, fit a new needle, prime it, turn the dose knob until it stops, then push and count to 5. Here is each step as the US leaflet gives it.1

  1. Wash your hands with soap and water.1
  2. Pull the cap straight off and check the pen. Don't use it if the name or strength doesn't match your prescription, it has expired, or it looks damaged.1 The medicine should be colourless to slightly yellow, never cloudy, frozen or with particles.1
  3. Wipe the red inner seal with an alcohol swab.1
  4. Fit a new pen needle. Push it straight on and twist until tight. Keep the outer needle shield; throw away the inner one.1
  5. Prime the pen. The next section has the detail.1
  6. Choose a site: thigh or belly, at least 5 cm (2 inches) from the navel. Someone else can use the back of your upper arm.1,7
  7. Set the dose. Turn the dose knob all the way until it stops and the dose symbol shows in the window. "Do not count clicks," the leaflet says.1
  8. Inject. Put the needle in, push the knob in until it stops, and slowly count to 5 while holding it.1
  9. Check. Pull the needle out. If the dose symbol isn't showing, put the needle back in and finish. Don't redial, and don't start again.1
  10. Tidy up. If you bleed, press lightly with cotton; don't rub. Put the outer shield back on, unscrew the needle into a sharps container, and recap the pen.1

A drop of medicine on the needle tip afterwards is normal and "will not affect your dose".1 If the knob is hard to push, the leaflet says to push more slowly. If the needle may be blocked, it says to fit a new one and prime again.1

Four doses, then a new pen. Each KwikPen holds 4 weekly doses of 0.6 mL, plus a little extra for priming.1,4 After the fourth dose, the pen won't let you dial a full dose. The leaflet says to throw it away "including the unused medicine".1

The leaflet also says "Do not inject the leftover medicine" and "Do not transfer MOUNJARO from your Pen into a syringe".1 The leaflet says never to share a pen, even with a new needle, because that can pass on a serious infection.1 Lilly's label says a person who can't see well needs a trained helper.1

Needles don't come with the KwikPen in the US or the EU.1,7 We couldn't confirm what's inside an Indian box, so check yours.

Why does the KwikPen need priming every week, and what about air bubbles?

Priming pushes out air and proves the pen works. Lilly's KwikPen leaflet says to do it "before each weekly injection", not only the first time.1

  • Turn the dose knob slowly until you hear 2 clicks and see the prime line in the window.1
  • Hold the pen needle-up and tap the cartridge holder gently "to collect air bubbles at the top".1
  • Push the knob in, count slowly to 5, and look for a drop at the needle tip. A drop means the pen is primed.1
  • No drop? The leaflet says to repeat up to 2 more times. Still none? It says to change the needle and try once more, then call the maker.1

The EU KwikPen leaflet has the same priming steps.7 Priming goes into the air, never into your body.1

Air bubbles elsewhere. Lilly's single-dose pen leaflet says "Air bubbles are normal."2 The US Ozempic prefilled syringe, a device we found no Indian listing for, has a leaflet saying bubbles "do not affect your dose" and not to try to remove them.5 With a vial and syringe, you tap bubbles to the top and push them out (next section).3

Warming the pen. Some how-to pages we checked say to take the pen out 30 minutes early. Lilly's single-dose pen leaflet says "It is not necessary to warm the Pen to room temperature."2 The KwikPen leaflet doesn't mention warming.1

How do the instructions say to inject from a Mounjaro vial?

The US single-dose vial leaflet says to draw 0.5 mL into a fresh syringe, push out the air bubbles, inject, and hold the needle in for at least 5 seconds.3

  1. Check the vial. Right medicine, right strength, not expired, not frozen, cloudy or with particles.3
  2. Prepare. Wash your hands. Flip off the plastic cap, but leave the rubber stopper in. Wipe the stopper with an alcohol swab.3
  3. Fill the syringe with air. With a new needle on, pull the plunger back to the 0.5 mL line. Push the needle through the stopper and inject that air into the vial.3
  4. Draw up the dose. Turn the vial and syringe upside down, keep the needle tip in the liquid, and pull past 0.5 mL.3
  5. Remove bubbles. Tap the syringe so bubbles rise. Push the plunger up to exactly the 0.5 mL line, then pull the syringe out.3
  6. Inject. Put the needle into your belly or thigh and push the plunger down. Keep it in for at least 5 seconds.3
  7. Finish. "Do not recap the needle." It goes straight into a sharps container.3

The US label says to use a syringe that can measure the dose, such as a 1 mL syringe.4 In the US, the syringe and needle are sold separately.3 The US label says to use a new syringe and needle every time.4

One vial is one dose. The leaflet says to throw it away after use, "even if there is medicine left in the vial".3 If you switch from vials to the KwikPen, the label asks for training on the new device.4

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What do the Ozempic pen instructions say, step by step?

The US Ozempic leaflet says to fit a new needle, remove both caps, check the flow with each new pen, dial your dose, then hold for 6 seconds.5

  1. Check the pen. Read the name and coloured label, especially if you use more than one medicine. The liquid should be clear and colourless.5
  2. Fit a new needle and remove both caps. "If you forget to remove both caps, you will not inject any medicine."5 Keep the outer cap.
  3. Check the flow (new pen only). Turn to the flow-check symbol, hold the pen needle-up, and press until the counter shows 0. A drop should appear.5
  4. Select your dose. Turn until the dose counter shows your dose, lined up with the pointer.5 "Do not set the dose by counting the number of clicks you hear."5
  5. Inject. Wipe the skin and let it dry. Put the needle in, keeping the counter visible, and press until it shows 0.5
  6. Hold for 6 seconds. Keep pressing and count slowly to 6. Pull out early and medicine may stream out, so you miss part of the dose.5
  7. Remove the needle. Unscrew it into a sharps container without recapping it, and put the pen cap back on. With no container, the leaflet describes a one-handed recap into the outer cap. Never put the inner cap back on.5

The flow check. If no drop appears, the leaflet says to repeat it up to 6 times. Then change the needle and try once more. Still nothing means don't use the pen.5

The dose counter. It also shows what's left: turn the selector until it stops.5 If it stops short of your dose, there isn't enough for a full dose, and the leaflet says to use a new pen.5

If the counter never reaches 0 while you press, the needle may be blocked. The leaflet warns you have then "not received any" medicine, even though the counter moved.5 The leaflet says to change the needle and repeat from step 1.5

The US pen comes with NovoFine Plus 32G 4 mm needles.5 Never use a syringe to draw medicine out of the pen, and don't leave it in a hot car.5 We couldn't confirm how many doses each Indian Ozempic pen holds; the counter tells you.

How is the Wegovy FlexTouch pen different?

It works like the Ozempic pen, with a flow check per new pen and a 6-second hold, but each pen gives one fixed strength.6,8

In the US, FlexTouch comes only as a 2.4 mg pen holding 4 doses. Lower US strengths are single-dose pens.6 In the EU, each FlexTouch pen holds 4 doses at every strength, from 0.25 mg to 2.4 mg.8 India's pens at 0.25, 0.5 and 1 mg are also called FlexTouch.12 We couldn't confirm how many doses each Indian Wegovy pen holds.

  • Flow check: before the first injection with each new pen only. If no drop appears, the leaflets say to check again, but "only … twice". Then change the needle once.6,8
  • Dose: turn until the counter stops at your dose. If it stops short, there isn't enough left, and the leaflet says to use a new pen.6
  • Inject: press until the counter shows 0, then keep pressing and count slowly to 6.6
  • Count your doses: the US leaflet asks you to use the table inside the carton lid.6 The US leaflet says the 2.4 mg pen goes after 4 doses, even if some medicine remains.6 We couldn't confirm the count for Indian pens.

Wegovy and Ozempic share a medicine, but not their dose steps. Wegovy vs Ozempic explains the difference.

Where do the instructions say to inject, and how do you rotate?

All three labels name the belly, thigh and upper arm, just under the skin. Each says to use a new spot every week.1,5,6

  • Belly: at least 5 cm (2 inches) from the navel.1,6
  • Thigh: the upper leg.1,6
  • Upper arm: Lilly's leaflets say another person should inject the back of your upper arm.1,2 Novo's labels list the upper arm without that condition.5,6

Rotating. You can stay in the same body area, but choose a different spot within it each week.1 Lilly says rotating lowers the risk of pits, thickened skin and lumps under the skin.3 India's ESI 2025 obesity guideline also says patients must be taught to avoid fatty lumps (lipohypertrophy).16

Lilly's vial leaflet says not to inject where the skin is tender, bruised, scaly, hard, scarred, pitted or lumpy.3 The Mounjaro Medication Guide says not to inject into a muscle or a vein.4 If you also use insulin, the Mounjaro label says to give it separately. It can go in the same area, but not right next to the Mounjaro.4

How often skin reacts. In Mounjaro's US trials, 3.2% had an injection-site reaction, vs 0.4% on a dummy injection (placebo).4 The EU Mounjaro leaflet lists itching or redness as "common" (up to 1 in 10 people).7 For Ozempic, the US figure was 0.2%.5

Get help now: call 112 if the face, lips, tongue or throat swell after an injection. Also call for trouble breathing or swallowing, or a severe rash. Lilly lists these as signs of a serious allergic reaction.4

Our short answer Where should you inject Ozempic or Mounjaro? covers sites alone.

How do you get rid of used needles and pens in India?

The US leaflets say used needles go straight into a hard, lidded container. Under India's 2026 waste rules, household needles are "special care waste", handed over separately.1,17

The US leaflets say never to throw loose needles in household rubbish.1,3 Without a proper sharps bin, they describe a household container that is:1,5

  • made of heavy-duty plastic;
  • closed with a tight, puncture-resistant lid that sharps can't come through;
  • upright and stable, and leak-resistant;
  • labelled to warn that it holds hazardous waste.

The leaflets also say don't recycle that container.1 A KwikPen with its needle removed can go in household rubbish, the US leaflet says.1 The Ozempic and Wegovy leaflets put the used pen in the sharps container too.5,6

The Indian rule. The Solid Waste Management Rules, 2026 were notified on 27 January 2026 and took effect on 1 April 2026.17,18 They list "used or waste needles and syringes" from homes as special care waste.17

Homes must sort rubbish into four streams: wet, dry, sanitary and special care. Each goes to authorised waste collectors.17 Special care waste is picked up by authorised agencies or dropped at designated collection centres.18

City bodies must set up one drop-off centre per 5 square kilometres and publish its timings.17 Your municipal office or waste collector can tell you where yours is. We found no separate CPCB guide for household sharps.

How long does a pen last once you start it?

A KwikPen lasts 30 days from first use or 4 doses, whichever comes first. The US Ozempic and Wegovy FlexTouch leaflets allow 56 days.1,5,6

  • Mounjaro KwikPen: after first use, up to 30°C; throw away 30 days after first use or after 4 doses.1,4
  • Ozempic pen: in use for 56 days at 15–30°C, or in the fridge.5
  • Wegovy FlexTouch (US): 56 days at 20–25°C or in the fridge. The leaflet says to throw it away if it has been above 30°C.6

All three leaflets say never store the pen with a needle on.1,5,6 Storage in heat gets its own post: Storing your pen in Indian heat, power cuts and travel. Guide 8 has the label rules now. Missed a week? See What to do if you miss a dose.

RisksThe medicine's risks, in brief
  • Stomach effects are the most common: nausea, diarrhoea, vomiting, constipation and belly pain (US Mounjaro and Ozempic labels).4,5
  • Pancreatitis: severe belly pain that won't go, sometimes spreading to the back.4
  • Gallbladder problems: 0.6% on Mounjaro vs 0% on placebo in US trials.4
  • Dehydration from vomiting or diarrhoea can lead to kidney injury.4
  • Thyroid warning: tirzepatide caused thyroid C-cell tumours in rats; the human relevance is unknown.4
  • Pregnancy: based on animal studies, it may harm an unborn baby.4
Full detail in Guide 5: Side effects and risks →

Mounjaro side effects by dose goes deeper.

Questions people ask

Do I need to prime the Mounjaro KwikPen every week?

Yes, according to Lilly's KwikPen instructions. They say to prime before each weekly injection, because priming removes air and checks the pen works.1

Can I use the medicine left in my KwikPen after 4 doses?

No. The instructions say to throw the pen away after 4 doses, leftover medicine included, and never to move it into a syringe.1

Is it a problem if I see air bubbles?

Lilly's single-dose pen leaflet says air bubbles are normal. For the KwikPen, priming clears them; with a vial, the leaflet says to tap them to the top and push them out.1,2,3

Do I check the Ozempic flow before every dose?

No. The Ozempic instructions say to check the flow only before the first injection with each new pen, or after dropping it.5

Can I reuse a pen needle?

No. Every leaflet says to use a new needle for each injection, to avoid infection and blocked needles.1,5

How do I throw away used needles in India?

The US leaflets say to keep them in a hard plastic container with a tight lid. India's 2026 waste rules class household needles as special care waste, collected separately.1,17

How we researched this

On 5–5 October 2026 we downloaded the current US labels for Mounjaro, Ozempic and Wegovy. They include each pen's and vial's Instructions for Use. We also read the EU product information for Mounjaro and Wegovy.

We searched Lilly and Novo Nordisk's Indian sites and found no Indian leaflet online. We read the Solid Waste Management Rules 2026 in the Gazette, and CDSCO's 2025 alert as a scanned letter. A pharmacy listing was used only to confirm vials are still listed; it is not linked.

Before you move on

  • The leaflet in your own box overrides anything here.
  • KwikPen: prime every week. Ozempic and Wegovy: flow check only with each new pen.
  • A new needle every time, and never share a pen.
  • Used needles go in a hard, lidded container, kept apart as special care waste.

More from the India blog

About GLP Guidebook

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An independent guide to GLP‑1 medicines. We don't sell medicines, take drug-company money or earn clinic commissions. Once a month: new brands, price changes, approvals, recalls and safety alerts. How we write

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Sources

  1. Eli Lilly and Company. Mounjaro KwikPen Instructions for Use, revised January 2026 (US label, not Indian). In the Mounjaro US labeling set. Link
  2. Eli Lilly and Company. Mounjaro single-dose pen Instructions for Use, revised April 2026 (US label, not Indian). Link
  3. Eli Lilly and Company. Mounjaro single-dose vial Instructions for Use, revised April 2026 (US label, not Indian). Link
  4. Eli Lilly and Company. Mounjaro US prescribing information, revised August 2026, and Medication Guide (US label, not Indian). PDF · Medication Guide
  5. Novo Nordisk. Ozempic US prescribing information (revised May 2026), Medication Guide and pen Instructions for Use (revised June 2026) (US label, not Indian). PDF
  6. Novo Nordisk. Wegovy US prescribing information and Wegovy FlexTouch Instructions for Use, revised June 2026 (US label, not Indian). PDF
  7. European Medicines Agency. Mounjaro product information: summary of product characteristics, package leaflet and KwikPen instructions (EU label, not Indian). Accessed 5 October 2026. PDF
  8. European Medicines Agency. Wegovy product information, including FlexTouch instructions (EU label, not Indian). Accessed 5 October 2026. PDF
  9. Business Standard (Rimjhim Singh, citing Reuters). Mounjaro KwikPen by Lilly debuts in India. Last updated 13 August 2025. Link
  10. Business Standard (Sohini Das, Reuters). Eli Lilly launches Mounjaro in India. 20 March 2025. Link
  11. PharmEasy Mounjaro product and price pages (single-dose vials and KwikPens listed), updated 1 October 2026, checked 5 October 2026. Cited as plain text, not linked.
  12. CDSCO, Enforcement & Intelligence Cell. Alert on theft of multiple drug products of M/s Novo Nordisk during transit. F. No. Enforc-11021(11)/46/2025-eoffice, 21 August 2025. PDF · archived copy
  13. Deccan Herald (PTI). Novo Nordisk launches anti-obesity drug Wegovy in India. 24 June 2025. Link
  14. Business Standard (Sanket Koul). Novo Nordisk cuts Ozempic, Wegovy prices in India. Last updated 1 April 2026. Link
  15. BioSpectrum India. Novo Nordisk India sets price of Rs 202 a day for starting dose of Ozempic and Wegovy (company announcement). 31 March 2026. Link
  16. Madhu SV, Kapoor N, Das S, Raizada N, Kalra S. ESI Clinical Practice Guidelines for the Evaluation and Management of Obesity in India: An Update (2025). Indian J Endocrinol Metab 2025. PMID 40917319. DOI
  17. Ministry of Environment, Forest and Climate Change. Solid Waste Management Rules, 2026. Gazette of India, S.O. 388(E), 27 January 2026: rule 3(zx) "special care waste", rule 5(1)(b). Copy hosted by OpenCity. PDF
  18. PIB (Ministry of Environment, Forest and Climate Change). New Solid Waste Management Rules notified; to come into force from April 1, 2026. January 2026. Link
  19. PIB Research (Government of India). GLP-1 drugs: use, risks, and regulation. 1 April 2026. PDF
  20. CDSCO. Recommendations of the Subject Expert Committee (Endocrinology & Metabolism), meeting of 20–21 April 2023. Item 1, tirzepatide. PDF · Archived copy
  21. CDSCO. Recommendations of the Subject Expert Committee (Endocrinology & Metabolism), meeting of 13–14 February 2024. Items 3–4, semaglutide. PDF · Archived copy

Last checked 5 Oct 2026 · Next review due 5 Oct 2027 · Report an error

How this post was made. Written by the GLP Guidebook team from the sources above. It's general information, not medical advice. Talk to a qualified doctor or nurse before your first injection, and before starting, stopping or changing any medicine. How we write