Can I take Mounjaro during Ramadan?
Yes, with planning, says advice for UK pharmacists. Citing international Ramadan guidance (IDF-DAR), it says injectable GLP-1s such as Mounjaro (tirzepatide) can continue through Ramadan in type 2 diabetes on a stable dose, and an injection does not break the fast. Evidence for weight-loss use is limited. Finish dose increases at least 4 to 6 weeks before Ramadan.
When should you stop raising the dose before Ramadan?
IDF-DAR and the South East London prescribing committee advise finishing dose increases at least 4 to 6 weeks before Ramadan, so side effects settle.1,2
If fasting starts soon, the advice is to hold off on the next dose increase.1 Any pause should be planned. Restarting at your old dose after a break may bring back stronger side effects.1 Fasting may be unsafe for some people, such as those on insulin or a sulfonylurea, those with recent severe low blood sugar, or during pregnancy.1
When should you inject during Ramadan?
The Pharmacist suggests injecting after Iftar, which may ease nausea, or after Suhoor, which may help you feel full through the fasting day.1
Keep the same injection day each week, and don't change the day and the dose together.1 The UK Mounjaro leaflet says you can move your injection day if at least 3 days have passed since your last dose.3 The same guidance says an injection does not break the fast.1
Wegovy tablets are different. They are taken on an empty stomach after at least 8 hours without food, with a sip of water, then nothing for 30 minutes.4 A tablet swallowed in fasting hours breaks the fast, so it has to fit the overnight eating window, ideally at Suhoor.1
Which risks go up when you fast on Mounjaro?
Fasting on a GLP‑1 raises the risk of dehydration, constipation and poor nutrition, and of low blood sugar with insulin or a sulfonylurea.1
The UK Mounjaro leaflet warns that vomiting, nausea or diarrhoea can cause dehydration, which may affect your kidneys.3 The Pharmacist suggests aiming for 1.5 to 2 litres of sugar-free fluid to rehydrate after Iftar.1 It says to break the fast straight away for low blood sugar, which Islamic guidance permits.1 Vomiting for more than 24 hours, or signs of dehydration, need a review.1 Full food and fluid advice is in Ramadan on Mounjaro or Wegovy.
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Sources
- Angela Carvalho. Fasting and weight-loss medications: what to advise your patients. The Pharmacist, 29 Jul 2026. Trade press (secondary), citing IDF-DAR 2021 and the NHS South East London Area Prescribing Committee. thepharmacist.co.uk
- Hassanein M et al. Diabetes and Ramadan: practical guidelines 2021 (IDF-DAR). Diabetes Res Clin Pract 2022;185:109185. Abstract read; GLP-1 advice taken from the summary in source 1. doi:10.1016/j.diabres.2021.109185 · PMID 35016991
- Eli Lilly. Mounjaro KwikPen (tirzepatide) UK patient information leaflet, last revised Aug 2026, sections 2, 3, 4 and 5. UK label. medicines.org.uk (emc)
- MHRA. First GLP-1 tablet for weight loss approved in the UK. Press release, 11 Jun 2026 ("As with all GLP-1 receptor agonists, this is a prescription-only medication"). gov.uk
- NHS. Dehydration (page last reviewed 1 May 2026). nhs.uk
- NHS. Diarrhoea and vomiting (page last reviewed 21 Dec 2023). nhs.uk
Last checked 12 Oct 2026 · Next review due 12 Oct 2027 · Report an error
How this answer was made. Written by the GLP Guidebook team from the sources above. It's general information, not medical advice. Talk to a qualified doctor before starting, stopping or changing any medicine. How we write