Can I fly with my GLP-1 pen?
Yes. TSA allows injectable medicines such as GLP-1 pens in carry-on bags, along with the unused needles or syringes that go with them, but you must declare them at the checkpoint. Ice packs to keep medicine cool are allowed even if melted. Keep pens at or below 86°F (30°C), the US label limit for Wegovy and Zepbound.
What are the TSA rules for GLP-1 pens?
TSA says “unused syringes are allowed when accompanied by injectable medication,” and that you “must declare these items” at the checkpoint.1
TSA allows larger amounts of medically necessary liquids “in reasonable quantities”, again declared for inspection.2 TSA says to tell the officer before screening and put medicines and their accessories in a separate bin.3
Ice packs, freezer packs and gel packs for medically necessary items can be “frozen, partially frozen or melted”.3 TSA recommends that medicine “be clearly labeled”, and the officer has the final say.4,2
How do you keep the pen within its temperature limit?
Keep it in your carry-on, below 86°F (30°C), and within the days your label allows out of the fridge.5,6
| Pen (US label) | Out of the fridge |
|---|---|
| Zepbound single-dose pen | Up to 21 days in total, up to 86°F (30°C)5 |
| Zepbound KwikPen | 30 days, up to 86°F (30°C)5 |
| Wegovy single-dose pen | Up to 28 days, 46°F to 86°F (8°C to 30°C)6 |
| Wegovy FlexTouch, after first use | 56 days, 59°F to 86°F (15°C to 30°C)6 |
Never use a pen that has frozen.5 The CDC advises packing medicines in your carry-on in case checked luggage is lost or delayed.7 Details for Zepbound are in How long can Zepbound stay out of the fridge?
What about flying abroad?
Check the rules of your destination, and of any country where you change planes, before you go.7
The CDC advises keeping medicines in their original labeled packs, carrying copies of your prescriptions with the generic names, and asking your prescriber for a note if you use injectable medicines.7 It suggests contacting the destination’s embassy to confirm your medicines are allowed.7
More on life with injections is in Guide 8.
Read the full picture
Related questions
Sources
- TSA. What can I bring? Unused syringes: “allowed when accompanied by injectable medication. You must declare these items.” tsa.gov
- TSA. What can I bring? Medications (liquid): medically necessary liquids “in reasonable quantities”, declared at the checkpoint. tsa.gov
- TSA. Disabilities and medical conditions (TSA Cares): ice packs and gel packs for medically necessary items; screening of syringes and supplies. tsa.gov
- TSA. “I am traveling with medication, are there any requirements I should be aware of?” (“It is recommended that medication be clearly labeled”). tsa.gov
- Eli Lilly. Zepbound (tirzepatide) US prescribing information, Medication Guide and Instructions for Use, revised 08/2026. US label. uspl.lilly.com
- Novo Nordisk. Wegovy (semaglutide) injection and tablets, US prescribing information and Medication Guide, revised 06/2026. US label. novo-pi.com
- CDC Travelers’ Health. Traveling abroad with medicine. Last reviewed Aug 18, 2022. cdc.gov
Last checked Oct 12, 2026 · Next review due Oct 12, 2027 · Report an error
How this answer was made. Written by the GLP Guidebook team from the sources above, all checked on Oct 12, 2026. It’s general information, not medical advice. Talk to a doctor, pharmacist or other licensed prescriber before starting, stopping or changing any medicine. In an emergency, call 911. How we write