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How much do Wegovy, Zepbound, Ozempic and other GLP-1s cost in the US over 6 or 12 months?

Pick who pays, a medicine and a dose plan. With insurance we add up your copay. On Medicare we add up the GLP-1 Bridge's $50 copay. Paying yourself, we add up the makers' own self-pay prices or the list price, month by month, with a source and date for every price. The result is a rough estimate to help you plan, not a quote.

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What this means

What this tells you

    What this doesn't mean

    • It isn't a quote, or a sign that a GLP-1 suits you. A licensed prescriber decides whether a medicine fits, which one and at what dose.
    • It isn't a sign your insurance or Medicare will pay. Plans decide coverage, usually through prior authorization, and Medicare decides who meets the Bridge criteria. The GLP-1 check explains what each route looks at.
    • It isn't what a telehealth service or clinic will charge. They set their own prices, and many add a membership fee. We don't show any seller's price or coupon.
    • It leaves out:
      • doctor or telehealth visit fees
      • your deductible, if you haven't met it yet
      • shipping, lab tests and other medicines
      • what happens after you stop

    Next steps

    Before you go further
    • GLP-1 medicines need a prescription from a prescriber licensed in your state. The FDA advises using a US state-licensed pharmacy that asks for a valid prescription.
    • Compounded semaglutide and tirzepatide are not FDA-approved and are not generics. The FDA doesn't review their safety, effectiveness or quality.
    • They have real risks, including:
      • stomach upsets
      • pancreatitis (an inflamed pancreas)
      • gallbladder problems
      • dehydration
      Read the risks
    • The FDA has found fake Ozempic pens in the US supply chain, most recently in December 2025.
    • Severe stomach pain that won't go away, with or without vomiting, can be pancreatitis. Call 911 or get emergency care. For a possible overdose, call Poison Control at 1-800-222-1222.

    Why we say this

    Every number in your result, and where it comes from. We use official sources: the makers' own published self-pay and list prices, the government site TrumpRx.gov, CMS for the Medicare GLP-1 Bridge, and the US labels for dose steps and pack sizes. The one price from a news report is labelled as such.

      How this works

      Paying yourself. Novo Nordisk and Lilly publish their own self-pay prices for people paying without insurance, for a month of medicine: 4 weekly doses, or 30 days of a daily tablet. We use the regular price for each dose. Time-limited offers and conditional prices, like Zepbound's $449 when every refill is within 45 days, are named in the notes but not added in, and we never use coupons or a seller's price. Some medicines have no maker self-pay price: we say so and show the list price only. The list price (wholesale acquisition cost) is the maker's price before insurers' discounts and rebates, from the maker's own price list or TrumpRx.gov.

      Months and fills. For weekly medicines we count 52 doses a year, so 12 months is 13 packs of 4. For daily medicines a month is the makers' 30 days: one bottle of 30 tablets. Daily pens (Saxenda, Victoza and generic liraglutide) hold 18 mg each, so we price them by the milligram from the pack: a month at 3 mg is 5 pens, and at 0.6 mg it is 1.

      The 2027 list-price cut. Novo Nordisk cuts the list price of Wegovy (pen up to 2.4 mg, and pill), Ozempic pens and Rybelsus to $675 a month from January 1, 2027. At the list price we count month 1 as this month, so months that fall in 2027 or later use $675. The announcement came before Wegovy HD 7.2 mg and Ozempic tablets, so they keep today's list price. Self-pay prices don't change.

      With insurance. You enter the copay your plan charges for one fill, and we multiply it by the number of fills: 13 a year for a weekly medicine (one every 28 days), 12 a year for daily medicines. Coverage for weight loss is optional: in 2025, 19% of firms with 200 or more workers covered GLP-1s mainly for weight loss, and 43% of firms with 5,000 or more, usually with prior authorization. Medicaid coverage depends on the state. Ozempic, Mounjaro, Trulicity, Rybelsus, Victoza and generic Victoza are approved for type 2 diabetes: plans cover them for diabetes, and using them for weight loss alone is off-label.

      Medicare. By law, Medicare drug plans can't cover medicines used only for weight loss. The GLP-1 Bridge is a separate CMS program from July 1, 2026 to December 31, 2027, with a $50 copay for each fill of Foundayo, Wegovy (pen or pill) or the Zepbound KwikPen. Single-dose Zepbound pens and vials, Saxenda, generic liraglutide and the diabetes medicines aren't covered; people with type 2 diabetes go through their Part D plan. We count fills from today, and any that fall after December 31, 2027 are left out, because nothing has been published about what comes after.

      Dose steps. "Label's dose steps" follows each US label: Wegovy pen 0.25, 0.5, 1 and 1.7 mg for 4 weeks each, then 2.4 mg; Zepbound and Mounjaro 2.5 mg, then up 2.5 mg at a time after at least 4 weeks; Ozempic 0.25 mg for 4 weeks, then 0.5, 1 and 2 mg; Trulicity 0.75, 1.5, 3 and 4.5 mg; the tablets step up every 30 days; liraglutide goes up 0.6 mg a week. Prescribers often go slower, and some people stay lower.

      My own plan. You set each step in whole weeks, starting from the label's steps; the last step runs to the end. A weekly medicine is 1 dose a week, so a 4-dose pack lasts 4 weeks, and a year is 52 weeks: 26 weeks is 6 months. A daily medicine is 7 doses a week, priced from its 30-day cost, so a week is 7/30 of a month. The tablets' 30-day label steps stay at 4 weeks and 2 days until you change them. Left as filled in, it gives the same total as the label's steps.

      What this can't tell you

      It can't tell you what your plan will approve, or which medicine or dose is right for you. Where we found no official price we show it as not published instead of guessing: there is no maker self-pay price for Saxenda, Victoza, Rybelsus, generic liraglutide or the Zepbound single-dose pen, and we found no published list price for the Zepbound single-dose pen or generic Victoza. Teva's generic Saxenda price comes from a news report. Saxenda and Rybelsus are being discontinued. Telehealth membership fees, visit fees and compounded products are left out on purpose.

      Questions people ask

      How much is Wegovy without insurance?

      Novo Nordisk's regular self-pay price is $349 a month for the Wegovy pen at any dose from 0.25 to 2.4 mg, and $399 for Wegovy HD 7.2 mg. A month is 4 pens. The Wegovy pill is $149 a month at 1.5 mg, $199 at 4 mg and $299 at 9 and 25 mg, for 30 tablets. New patients pay $199 for the first 2 months of the pen, an offer that runs through December 31, 2026. The list price is $1,349.02 a month, falling to $675 from January 1, 2027. Prices checked Oct 12, 2026.

      How much is Zepbound without insurance?

      Lilly's regular self-pay price for the Zepbound KwikPen or vials is $299 a month at 2.5 mg, $399 at 5 mg, $499 at 7.5 mg and $699 at 10 to 15 mg. $449 if every refill is within 45 days. The single-dose pen has no self-pay price: Lilly sells it through insurance. Only the KwikPen is covered by the Medicare GLP-1 Bridge. Prices checked Oct 12, 2026.

      How much are Ozempic and Mounjaro without insurance?

      Both are approved for type 2 diabetes; using them for weight loss is off-label. Novo Nordisk's self-pay price for the Ozempic pen is $349 a month for 0.25, 0.5 or 1 mg and $499 for 2 mg, and the Ozempic pill is $149 to $299. Lilly's self-pay price for Mounjaro is $499 a month at every dose. List prices are $1,027.51 for Ozempic and $1,112.16 for Mounjaro. Prices checked Oct 12, 2026.

      What does the Medicare GLP-1 Bridge cost?

      $50 a month for Wegovy (pen or pill), Foundayo or the Zepbound KwikPen, from July 1, 2026 to December 31, 2027, for people who meet the CMS criteria. Other medicines and forms, including Zepbound vials and single-dose pens, Saxenda and the diabetes medicines, aren't covered. It runs outside Part D, so the Part D deductible doesn't apply. The prescriber sends the request and Medicare decides who is eligible.

      Is this what I'll actually pay?

      Treat it as a rough estimate, not a quote. It uses the makers' published regular prices, list prices, the copay you enter or the Bridge's $50, and the label's dose steps. Your plan, your pharmacy, how your dose changes and what your coverage approves can all move the real figure.

      Why doesn't the calculator use coupons or telehealth prices?

      We only use official prices: the makers' published self-pay prices, list prices from the makers and the government site TrumpRx.gov, and the Medicare copay set by CMS. One exception: Teva hasn't published its generic Saxenda price, so we use the figure a Teva spokesperson gave Fierce Pharma, and say so. Savings cards depend on your insurance, conditional prices depend on refill timing, and telehealth services set their own prices, so we leave them out and never show a seller's price.

      Why does the monthly cost go up after the first months?

      The label raises the dose in steps, and some self-pay prices are higher at higher doses. An insurance copay, or the Bridge's $50, usually stays the same whatever the dose.

      Sources

        Prices checked · Re-checked monthly · US price data is kept in this page

        GLP Guidebook is an independent guide. We name brands and official prices as facts. We don't recommend any brand, company or seller, and we earn nothing from them. Written from published sources. General information, not medical advice.